Integron Containing CR1 and blaCTX-M-2 and Associated with a Tn21-Like Element
نویسندگان
چکیده
In117, an Unusual In0-Like Class 1 Integron Containing CR1 and blaCTX-M-2 and Associated with a Tn21-Like Element Aránzazu Valverde, Rafael Cantón, Juan Carlos Galán, Patrice Nordmann, Fernando Baquero, and Teresa M. Coque* Hospital Universitario Ramón y Cajal, IMSALUD, Madrid, Spain, and Service de Bactériologie-Virologie, Hôpital de Bicêtre, Assistance Publique/Hôpitaux de Paris, Faculté de Médecine Paris-Sud, Université 9 Paris XI, K.-Bicêtre, France
منابع مشابه
First detection of plasmid-mediated quinolone resistance in the community setting and in hospitalized patients in Switzerland.
1. Eckert C, Gautier V, Arlet G. DNA sequence analysis of the genetic environment of blaCTX-M genes. J Antimicrob Chemother 2006; 57: 14–23. 2. Cantón R, Coque TM. The CTX-M b-lactamase pandemic. Curr Opin Microbiol 2006; 9: 466–75. 3. Partridge SR, Hall RM. In34, a complex In5 family class 1 integron containing orf513 and dfrA10. Antimicrob Agents Chemother 2003; 47: 342–9. 4. Valverde A, Cant...
متن کاملTransposon Tn21, flagship of the floating genome.
The transposon Tn21 and a group of closely related transposons (the Tn21 family) are involved in the global dissemination of antibiotic resistance determinants in gram-negative facultative bacteria. The molecular basis for their involvement is carriage by the Tn21 family of a mobile DNA element (the integron) encoding a site-specific system for the acquisition of multiple antibiotic resistance ...
متن کاملTn5060 from the Siberian permafrost is most closely related to the ancestor of Tn21 prior to integron acquisition.
A Tn21-related mercury resistance transposon, Tn5060, has been isolated from Pseudomonas sp. strain A19-1 from a 8,000-10,000-year-old Siberian permafrost sample, and sequenced. Like Tn21, the element transposes to different plasmids at a frequency of 10(-2)-10(-3) per target plasmid transfer. Comparison of the complete Tn5060 DNA sequence (8,667 bp) with that of Tn21 (19,672 bp) shows that Tn5...
متن کاملThe bla(CTX-M-1) gene located in a novel complex class I integron bearing an ISCR1 element in Escherichia coli isolates from Zhenjiang, China.
Sir, CTX-M enzymes include more than 60 variants belonging to five different clusters (CTX-M-1, CTX-M-2, CTX-M-8, CTX-M-9 and CTX-M-25) according to their amino acid sequence. In recent years, CTX-M enzymes have become the most prevalent extended-spectrum b-lactamases (ESBLs), both in nosocomial and in community settings. Different genetic elements might be involved in the mobilization of blaCT...
متن کاملA novel dihydrofolate reductase cassette inserted in an integron borne on a Tn21-like element.
In this study, a 498-bp dhfrXII gene coding for trimethoprim resistance was found inserted in a cassette-like manner in the recombinationally active locus, the integron, borne on a transposon Tn21-like element. The dhfrXII cassette is distinct from those cassettes earlier observed in integrons and was found here upstream of two similarly inserted cassettes. The second one carried the new uniden...
متن کامل